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TreeAzin Systemic Insecticide is owned by the Canadian Forest Service (CFS) and was developed in collaboration with BioForest. TreeAzin is a systemic insecticide produced from Neem tree (Azadiracta indica) seed extracts that is injected directly into the base of trees. TreeAzin is not a neonicotinoid and is not from the avermectin family of pesticides.

TreeAzin is effective against a variety of insects that consume tree tissues. In Canada, TreeAzin (PCP 30559) is registered by Health Canada’s Pest Management Regulatory Agency (PMRA) for the control of: Emerald Ash Borer, Gypsy Moth, Tent Caterpillars, Spruce Budworm, Jack Pine Budworm, Arborvitae Leafminers, Sawflies, including Birch Leafminer and Introduced Pine Sawfly, European Elm Scale, and Red Elm Bark Weevil. Ontario’s Ministry of Environment, Conservation and Parks (MOECP) scheduled TreeAzin as a class C pesticide and can be applied by licensed exterminators. It is also listed by the Organic Materials Review Institute (OMRI) for organic use and is exempt from Ontario’s Cosmetic Pesticide Ban Act.

Research trials are underway testing the effectiveness of TreeAzin against insect pests other than those listed above. BioForest will continue to communicate developments as more science-backed information becomes available.

Affordability of Treatment

TreeAzin treatment almost always costs less than the cost of tree removal, disposal and replanting, and is competitive with other treatment options, without sacrificing environmental safety. Additionally, utilizing BioForest’s EcoJect System allows for multiple, simultaneous tree injections, yielding industry leading high volume efficiencies and scalability in larger treatment programs.

Related Pest & Pathogens

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TreeAzin Systemic Insecticide

The product label contains directions, application rates and types of pests.

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TreeAzin Systemic Insecticide

This Safety Data Sheet contains occupational safety and health data for this product.

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  • TreeAzin is a systemic insecticide injected directly into the base of trees.
  • TreeAzin is produced from Neem tree (Azadiracta indica) seed extracts.
  • Neem extracts have been used for centuries to control insects.
  • The active ingredient in TreeAzin is Azadirachtin (5% solution).
  • TreeAzin is NOT Neem Oil.
  • In Canada, TreeAzin is registered by Health Canada’s Pest Management Regulatory Agency (PMRA) (PCP 30559).
  • TreeAzin is exempt from Ontario’s Cosmetic Pesticide Ban Act.
  • In the United States, TreeAzin is registered by the Environmental Protection Agency (EPA) as a bioinsecticide (Reg. No. 82996-1). It is also listed by the Organic Materials Review Institute (OMRI) for use in organic crops.
  • TreeAzin is owned by the Canadian Forest Service (CFS) and was developed in collaboration with BioForest, who holds its worldwide license.
  • Always read the TreeAzin Label before using.
  • TreeAzin is injected under a tree’s bark, directly into the conductive tissues, and moves upwards with the flow of water and nutrients.
  • TreeAzin is formulated to inject quickly into ash (avg. 15 – 30 min. / tree) and translocates rapidly throughout the tree (approx. 48 hrs).
  • TreeAzin controls insect larvae feeding on the tree’s tissues by regulating growth and disrupting normal molting.
  • In certain groups of insect pests, like Emerald Ash Borer, TreeAzin has also been shown to reduce fertility and egg viability when adult females feed on a treated tree’s foliage.
  • These multiple modes of action help to reduce the potential for resistance in pest populations.
  • TreeAzin is found throughout the tree at effective levels through the growing season and provides up to two years’ protection against Emerald Ash Borer.
  • Early summer injections (5 ml/cm dbh) provide effective control of EAB for up to two seasons.
  • In the year of treatment:
    • 95% EAB larvae feeding on treated tree tissues do not complete development and die
    • Adult female EAB beetles that feed on treated tree leaves lay significantly fewer eggs
    • Eggs laid are not viable (<1% viable)
  • In the year following treatment:
    • EAB larvae hatched from viable eggs do not complete development
    • Number and length of EAB galleries are significantly lower in treated vs. untreated ash

TreeAzin is effective against a variety of insects that consume tree tissues.

In Canada, TreeAzin (PCP 30559) is registered by Health Canada’s Pest Management Regulatory Agency (PMRA) for the control of:

  • Emerald Ash Borer
  • European Elm Scale
  • Gypsy Moth, Tent Caterpillars, Spruce Budworm, Jack Pine Budworm
  • Arborvitae Leafminers
  • Red Elm Bark Weevil
  • Birch Leaf Miner
  • Pine false Webworm
  • Introduced Pine Sawfly

In the United States, TreeAzin (EPA Registration Number 82996-1) is registered by Environmental Protection Agency (EPA) for the control of:

  • Emerald Ash Borer
  • Scales (e.g. European Elm Scale, Kermes Scale, Elongate Hemlock Scale, Gloomy Scale)
  • Defoliator (e.g. Gypsy Moth, Tent Caterpillars, Canker Worm, Spruce Budworm, Jack Pine Budworm, Winter Moth, Brown Tail Moth)
  • Adelgids (e.g. Hemlock Woolly Adelgid, Balsam Woolly Adelgid)
  • Aphids (e.g. Linden Aphids)
  • Beetles (e.g. Elm Leaf Beetle, Japanese Beetle)
  • Weevils (e.g. Beech Leaf Mining Weevil, Red Elm Bark Weevil, White Pine Weevil)
  • Sawflies (e.g. Birch Leaf Miner, Arborvitae Leaf Miners, Pine False Webworm)
  • When used as labeled, TreeAzin poses minimal risk to:
    • applicators, bystanders, and pets
    • bees, birds, and mammals
    • soil and aquatic ecosystems
  • TreeAzin is injected under a tree’s bark, directly into the conductive tissues.
  • TreeAzin degrades naturally within tree tissues.
  • According to a 2010 Canadian Forest Service publication, the botanical origin of TreeAzin, coupled with its low risk toxicological characteristics, makes it suitable for use in urban settings and environmentally sensitive areas.
  • TreeAzin is injected under a tree’s bark, directly into the conductive tissues, and moves upwards with the flow of water and nutrients.
  • BioForest has developed the EcoJect System, a tree microinjection system for the application of systemic pesticides into high value trees (US Patent 7,114,289).
  • With the EcoJect System:
    • Canisters are loaded with TreeAzin and sealed under pressure.
    • Small injection holes (15/64″) are drilled into the tree (3/4 – 1″).
    • Nozzles are inserted and secured in the injection holes.
    • TreeAzin loaded canisters are mated with the nozzles, beginning the injection.
    • TreeAzin is formulated to inject quickly into ash (avg. 15 – 30 min. / tree) and translocates rapidly throughout the tree (approx. 48 hrs).
  • The dosage rate and number of injection sites per tree depends on the insect being controlled and on the health and size of the ash tree.
  • Consult an expert to determine treatment requirements for your tree.

TreeAzin may only be applied by professional licensed pesticide applicators.

DO NOT DELAY, have your tree assessed by a qualified service provider as soon as possible.

BioForest has a searchable listing of licensed pesticide applicators offering TreeAzin treatment services for Emerald Ash Borer and other insect pests.

It is advisable to contact multiple service providers for quotes, as many work outside of their immediate office location and set their own treatment prices.

If you’re a tree care professional looking into becoming a licensed exterminator to start a Plant Health Care program, please contact your local pesticide regulatory agency.

TreeAzin treatment costs depend on a number of factors including the insect pest of concern, the degree of insect infestation, and the size, health, and location of a tree.

For Emerald Ash Borer, to be effective, TreeAzin treatments should be conducted every two years while populations persist.

The cost of treating and maintaining a tree’s benefits are often less than the cost of removing, disposing, and replanting.

Among many other benefits, urban trees reduce air and noise pollution, increase property value, help reduce stress, provide wildlife habitat, and add beauty to a community. It takes roughly 30 years for a newly planted tree to begin providing maximum benefits to the urban forest.

BioForest does not set TreeAzin treatment prices. It is advisable to contact multiple service providers for quotes.

• Drilling through the outer bark creates a wound in the tree.

• The response of the tree to these wounds is affected by factors such as the size and depth of the hole and the vigor of the tree.

• In a recent study, ash trees that were healthy and injected with TreeAzin using the EcoJect System in 2008 showed little evidence of damage a year following treatment.

• New, healthy wood was produced over the injection sites and there was no evidence of pathogen infection, decay, or other signs of serious injury.

• Treating an ash tree with TreeAzin to protect it from Emerald Ash Borer does not guarantee its survival, but an untreated ash tree will almost certainly die.

• Health Canada’s Pest Management Regulatory Agency (PMRA) granted TreeAzin registration in 2012 (PCP 30559).

• The U.S. Environmental Protection Agency (EPA) registered TreeAzin as a bioinsecticide in 2008 and it has since been registered in some 30 states (Reg. No. 82996-1).

• TreeAzin is listed by the Organic Materials Review Institute (OMRI) for use in organic crops.

When EAB populations are low in years one to five of an EAB outbreak, biennial treatments (every two years) are appropriate to protect ash trees. As EAB populations increase exponentially and are high in years 6 to 11 of an outbreak, treating two out of every three years is recommended to effectively protect the tree from the growing EAB pressure. Once EAB populations are in decline beyond year 11, biennial treatments can resume as part of the maintenance phase. Following this strategy, trees are better protected when EAB populations peak, and result in only one additional treatment versus a biennial treatment strategy.

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Diameter at Breast Height (DBH) & Canister Placement

Learn how to measure DBH for dose rates and canister placement for proper distribution of product.

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Environmental Impact of TreeAzin

Learn the product environmental risk factors.

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TreeAzin Tech Sheet

Learn more about technical information about TreeAzin.

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Treatment Strategies

Learn how to situation yourself in a EAB population outbreak.

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